Edible vaccines are particularly beneficial for developing regions, where healthcare resources are limited. They are economical to produce and can be grown locally, reducing dependency on centralized manufacturing facilities. Their heat-stability eliminates the need for cold chain storage, addressing a major logistical challenge in vaccine distribution. Oral administration simplifies the vaccination process, making it accessible in areas lacking trained healthcare professionals. These features make edible vaccines a practical solution for immunizing populations in remote or underserved areas. By overcoming barriers faced by traditional vaccines, they hold promise for improving health outcomes in communities most vulnerable to infectious diseases.